About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3603039
Allelic
Composition		 Ewsr1tm1(ERG)Thr/Ewsr1+
Rag1tm1(cre)Thr/Rag1+
Genetic
Background		 involves: 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ewsr1tm1(ERG)Thr mutation (0 available); any Ewsr1 mutation (93 available)
Rag1tm1(cre)Thr mutation (0 available); any Rag1 mutation (133 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased leukemia incidence ( J:98679 )
• mutant mice develop leukemia involving T cells with infiltrating lymphoblasts in the bone marrow, liver, and kidney

immune system
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased lymphocyte cell number ( J:98679 )
• associated with leukemia

hematopoietic system
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia
increased lymphocyte cell number ( J:98679 )
• associated with leukemia

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:98679 )
• associated with leukemia

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory