About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3590415
Allelic
Composition
Itgb2tm1Bay/Itgb2tm2Bay
Genetic
Background
PL.129S7-Itgb2tm1Bay Itgb2tm2Bay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb2tm1Bay mutation (1 available); any Itgb2 mutation (9 available)
Itgb2tm2Bay mutation (3 available); any Itgb2 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• Background Sensitivity: develop moderate to severe psoriasiform dermatitis on the PL/J background but not on the C57BL/6J background

integument
• Background Sensitivity: develop moderate to severe psoriasiform dermatitis on the PL/J background but not on the C57BL/6J background
• Background Sensitivity: compound heterozygous mice develop chronic inflammatory skin disease on the PL/J background but not a C57BL/6J background
• lesions are multifocal or patchy

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
psoriasis DOID:8893 OMIM:PS177900
J:84126


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/19/2020
MGI 6.15
The Jackson Laboratory