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Phenotypes Associated with This Genotype
Genotype
MGI:3589794
Allelic
Composition		 Dgkitm1Mtop/Dgkitm1Mtop
Tg(Hba-x-v-Ha-ras)TG.ACLed/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dgkitm1Mtop mutation (0 available); any Dgki mutation (39 available)
Tg(Hba-x-v-Ha-ras)TG.ACLed mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of induced tumors ( J:99817 )
• skin tumors induced by application of PMA or by full-thickness skin wounding are fewer in Dgkitm1Mtop homozygotes carrying the v-Ha-ras transgene compared to wild-type, transgene-positive mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory