Phenotypes for Mgp Spp1 MGI:3589019 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mgp^tm1Kry/Mgp^tm1Kry Spp1^tm1Blh/Spp1⁺
Genetic Background	involves: Black Swiss * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mgp^tm1Kry mutation (1 available); any Mgp mutation (11 available)
Spp1^tm1Blh mutation (2 available); any Spp1 mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:79746 )

• mice homozygous for Mgp^tm1Kry and heterozygous for Spp1^tm1Blh start to die during weeks 3 and 4 after birth as a result of vascular rupture and subsequent internal hemorrhage

cardiovascular system

calcified artery ( J:79746 )

internal hemorrhage ( J:79746 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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