Phenotypes for Gdnf Nrtn MGI:3588573 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gdnf^tm1Rosl/Gdnf^tm1Rosl Nrtn^tm1Jmi/Nrtn^tm1Jmi
Genetic Background	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdnf^tm1Rosl mutation (0 available); any Gdnf mutation (20 available)
Nrtn^tm1Jmi mutation (1 available); any Nrtn mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal enteric ganglia morphology ( J:82456 )

• severe intestinal aganglionosis, similar to that seen in single homozygous Gdnf^tm1Rosl mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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