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Phenotypes Associated with This Genotype
Genotype
MGI:3588063
Allelic
Composition
Thrbtm2Few/Thrbtm2Few
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thrbtm2Few mutation (0 available); any Thrb mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• learning deficit identified in a Morris water maze tes

nervous system
• reduced branching
• changes similar to those seen in congenital hypothyroidism

homeostasis/metabolism
• 3 fold elevation over levels seen in Thrbtm1Df homozygotes

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
thyroid hormone resistance syndrome DOID:11633 OMIM:188570
OMIM:274300
J:77623


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory