Phenotypes Associated with This Genotype

Genotype
MGI:3586705

• Allelic Composition: Fzd9^tm1Sjp/Fzd9⁺
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal forebrain development ( J:99893 )

• at E14.5, there is a slight increase, less than that in homozygotes, in M-phase precursor cells in the medial cortical wall compared to wild-type mice

• at E14.5, the number of apoptotic cells in the dentate analage is less than in homozygotes but still increased compared to wild-type mice

abnormal dentate gyrus morphology ( J:99893 )

• a decrease in the number of dentate granule cells and an increase in the hilar mossy cell number, intermediate to that detected in homozygous mutants, are seen