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Phenotypes Associated with This Genotype
Genotype
MGI:3584118
Allelic
Composition		 Tg(Col2a1-GAL4)1Amc/0
Tg(UAS-Smo*W539L)1Amc/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal long bone epiphyseal plate proliferative zone ( J:73071 )
• 20% increase in chondrocyte proliferation at E14.5 and 60% increase at E16.5 in the proliferative zone of the tibia, mainly in the region close to the articular surface of the cartilage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory