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Phenotypes Associated with This Genotype
Genotype
MGI:3583772
Allelic
Composition
Ccd/Ccd+
Genetic
Background
B10Rl.101-Ccd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• mostly on the right side though seen bilaterally and also on the left
• incomplete clavicles
• 18 of 31 show greatly indented anterior border of the scapula on the left side
• 17 of 31 have one or more ischia that are crooked (bent laterally) and all have an ischium and pubis that do not connect on at least one side of the body
• all have an ischium and pubis that do not connect on at least one side of the body
• tear- or comet-shaped hole between the frontals and parietals
• interparietal bone is divided into 2 or more pieces and the width and length is decreased by 23% and 16%, respectively
• 6 of 31 show interparietal-occipital fusion
• absent or greatly reduced ventral branch of the posttympanic hook of the squamosal
• large gap between the jugal and squamosal bones making the orbit around the eye incomplete
• jagged edge at anterior end of nasals caused by absence of bone
• xiphisternum is 50-75% of the normal length, wider than normal, and is curved ventrally
• incomplete penetrance of dorsal dyssymphysis of the 9 most anterior vertebrae

craniofacial
• tear- or comet-shaped hole between the frontals and parietals
• interparietal bone is divided into 2 or more pieces and the width and length is decreased by 23% and 16%, respectively
• 6 of 31 show interparietal-occipital fusion
• absent or greatly reduced ventral branch of the posttympanic hook of the squamosal
• large gap between the jugal and squamosal bones making the orbit around the eye incomplete
• jagged edge at anterior end of nasals caused by absence of bone

limbs/digits/tail
• mostly on the right side though seen bilaterally and also on the left

vision/eye
• large gap between the jugal and squamosal bones making the orbit around the eye incomplete

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
cleidocranial dysplasia DOID:13994 OMIM:119600
OMIM:216330
J:16170


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2021
MGI 6.16
The Jackson Laboratory