Phenotypes for St8sia4 MGI:3582290 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	St8sia4^tm1Crem/St8sia4^tm1Crem
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St8sia4^tm1Crem mutation (0 available); any St8sia4 mutation (28 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

reduced long-term potentiation ( J:63481 )

• adult, but not young, homozygous null mice exhibit impaired long term potentiation in hippocampal CA1 synapses but not CA3 synapses

reduced long-term depression ( J:63481 )

• adult, but not young, homozygous null mice exhibit impaired long term depression in hippocampal CA1 synapses

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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