Mouse Genome Informatics
cx
    Itgb6tm1Des/Itgb6tm1Des
Mmp12tm1Sds/Mmp12tm1Sds

involves: 129/Sv * 129T2/SvEms
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
immune system
• degree of lung inflammation was similar to that in single homozygous Itgb6 mutant mice

respiratory system
N
• did not exhibit alveolar enlargement and did not develop emphysema (J:89578)
• degree of lung inflammation was similar to that in single homozygous Itgb6 mutant mice

integument
• developed patchy juvenile baldness associated with skin inflammation

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Emphysema, Hereditary Pulmonary 130700 J:89578