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Phenotypes Associated with This Genotype
Genotype
MGI:3581437
Allelic
Composition
Itgb6tm1Des/Itgb6tm1Des
Genetic
Background
involves: 129T2/SvEms
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb6tm1Des mutation (0 available); any Itgb6 mutation (12 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
respiratory system
• normal alveolar size at 2 months of age, however spontaneously developed progressive alveolar enlargement over time
• developed pulmonary emphysema over time

Mouse Models of Human Disease
OMIM ID Ref(s)
Emphysema, Hereditary Pulmonary 130700 J:89578


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory