Phenotypes Associated with This Genotype

Genotype
MGI:3579788

• Allelic Composition: Pcp2^tm1Jim/Pcp2^tm1Jim
• Genetic Background: involves: 129S1/Sv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:40442 )

• appeared normal at birth and developed through adulthood without any behavioral signs of cerebellar or retinal degeneration or dysfunction

• anatomically, cerebellar foliation and cortical structure was normal

• the cerebellar nuclei and brainstem structures that innervate the cerebellum, such as inferior olivary nucleus appeared normal

• number of Purkinje neuron were normal

• no evidence of any enhanced Purkinje cell loss in 1 year old mutant mice