Mouse Genome Informatics
hm
    Mdktm1Tmu/Mdktm1Tmu
B6.129S2-Mdktm1Tmu
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
immune system
• following partial hepatectomy (PH), macrophage infiltration into the liver is decreased
• following partial hepatectomy (PH), neutrophil infiltration into the liver is decreased

behavior/neurological
N
• mice exhibit normal locomotor activity and acoustic startle reactivity (J:151029)
• mice make less frequent contacts, longer times in total contacts, and longer times per one contact compared with wild-type mice

nervous system
• in the striatum
• however, prepubertal mice and mice treated with haloperidol or clozapine exhibit normal prepulse inhibition
• adult mice exhibit reduced prepulse inhibition compared with wild-type mice

hearing/vestibular/ear
• mice experience low to moderate levels of auditory deficits

homeostasis/metabolism
• following partial hepatectomy (PH), amino-transferase levels are decreased
• in the striatum
• less severe adhesions of the intestine after partial hepatectomy (50% as opposed to 100%)
• omental adhesions reduced after peritoneal wall injury

liver/biliary system
• one day following partial hepatectomy (PH)

hematopoietic system
• following partial hepatectomy (PH), macrophage infiltration into the liver is decreased
• following partial hepatectomy (PH), neutrophil infiltration into the liver is decreased

cellular
• following partial hepatectomy (PH), macrophage infiltration into the liver is decreased
• following partial hepatectomy (PH), neutrophil infiltration into the liver is decreased

Mouse Models of Human Disease
OMIM IDRef(s)
Schizophrenia; SCZD 181500 J:151029