Phenotypes Associated with This Genotype

Genotype
MGI:3577617

• Allelic Composition: Pcgf2^tm1Hko/Pcgf2^tm1Hko; Bmi1^tm1Brn/Bmi1⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial bone morphology ( J:68216 )

split exoccipital bone ( J:68216 )

cleft secondary palate ( J:68216 )

skeleton

abnormal scapula morphology ( J:68216 )

acromion hypoplasia ( J:68216 )

• acromion is poorly formed

scapular bone foramen ( J:68216 )

• holes are seen in the blade of the scapula

abnormal axial skeleton morphology ( J:68216 )

abnormal craniofacial bone morphology ( J:68216 )

split exoccipital bone ( J:68216 )

abnormal rib joint morphology ( J:68216 )

• rudimentary ribs attached to C6

abnormal cervical atlas morphology ( J:68216 )

• atlas resembles the third cervical vertebra

cervical vertebral transformation ( J:68216 )

• atlas resembles the third cervical vertebra

abnormal sternum ossification ( J:68216 )

• ectopic ossification centers in sternum

digestive/alimentary system

cleft secondary palate ( J:68216 )

growth/size/body

cleft secondary palate ( J:68216 )