Phenotypes Associated with This Genotype

Genotype
MGI:3574995

• Allelic Composition: Mt3^tm1Rpa/Mt3^tm1Rpa; Tg(SOD1*G93A)^dl1Gur/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:79760 )

• markedly reduced survival, by about 20%

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:79760 )

• severe declines in motor function starting around 5-6 months of age

decreased grip strength ( J:79760 )

• reduced

nervous system

decreased motor neuron number ( J:79760 )

• becomes severe after mice begin to display behavioral symptoms