About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3573951
Allelic
Composition		 Cd8atm1Mak/Cd8atm1Mak
Zbtb7bhd/Zbtb7bhd
Genetic
Background		 involves: B6.129S2-Cd8atm1Mak * B6.Cg-Thpokhd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8atm1Mak mutation (7 available); any Cd8a mutation (37 available)
Zbtb7bhd mutation (0 available); any Zbtb7b mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
absent CD4-positive, alpha-beta T cells ( J:95867 )
• lack mature, single-positive CD4+ thymocytes or peripheral CD4+ T cells

immune system
absent CD4-positive, alpha-beta T cells ( J:95867 )
• lack mature, single-positive CD4+ thymocytes or peripheral CD4+ T cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory