Phenotypes Associated with This Genotype

Genotype
MGI:3527868

• Allelic Composition: Cx3cl1^tm1Sgs/Cx3cl1^tm1Sgs
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased cerebral infarct size ( J:95634 )

• infarct size was reduced by 28% and significantly lower mortality was seen in homozygotes compared to wild-type mice after middle cerebral artery occlusion

• however, the brain and surface cerebral arteries are not significantly different in homozygotes compared to wild-type mice

homeostasis/metabolism

decreased cerebral infarct size ( J:95634 )

• infarct size was reduced by 28% and significantly lower mortality was seen in homozygotes compared to wild-type mice after middle cerebral artery occlusion

• however, the brain and surface cerebral arteries are not significantly different in homozygotes compared to wild-type mice