About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3525494
Allelic
Composition		 Mmp3tm1Mrl/Mmp3tm1Mrl
Timp1tm1Pds/Timp1tm1Pds
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmp3tm1Mrl mutation (0 available); any Mmp3 mutation (32 available)
Timp1tm1Pds mutation (1 available); any Timp1 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to bacterial infection ( J:94836 )
• after infection, inflammation is resolved and corneal integrity restored unlike in C57BL/6 wild-type mice, however resistance is decreased compared to Timp1 single homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory