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Phenotypes Associated with This Genotype
Genotype
MGI:3525186
Allelic
Composition		 Notch1tm2Rko/Notch1tm2Rko
Notch3Gt(PST033)Byg/Notch3Gt(PST033)Byg
Tg(Msx2-cre)5Rem/0
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1tm2Rko mutation (3 available); any Notch1 mutation (116 available)
Notch3Gt(PST033)Byg mutation (0 available); any Notch3 mutation (96 available)
Tg(Msx2-cre)5Rem mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal hair follicle morphology ( J:94517 )
• displayed similar follicular morphologies as mutant mice homozygous for Notch1tm1Shn expressing the Tg(Msx2-cre)5Rem transgene

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory