Phenotypes Associated with This Genotype

Genotype
MGI:3522037

• Allelic Composition: Nqo2^tm1Akj/Nqo2^tm1Akj
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased skin tumor incidence ( J:92400 )

• in two stage tests increased sensitivity to chemically induced tumors

hematopoietic system

abnormal lymphopoiesis ( J:80549 )

• reduced numbers of circulating lymphocytes

increased granulocyte number ( J:80549 )

thrombocytosis ( J:80549 )

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:80549 )

• less susceptible to vitamin K3 toxicity (menadione)

immune system

abnormal lymphopoiesis ( J:80549 )

• reduced numbers of circulating lymphocytes

increased granulocyte number ( J:80549 )

integument

increased skin tumor incidence ( J:92400 )

• in two stage tests increased sensitivity to chemically induced tumors