Phenotypes Associated with This Genotype

Genotype
MGI:3513138

• Allelic Composition: Mitf^Mi/Mitf⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:125080 )

• slight dilution of the fur in the young returns to normal in the adult

white spotting ( J:125080 , J:30758 )

• some, but not all, heterozygotes have a small spot on the head between the eyes and ears or spots on the belly or tail (J:125080)

• white regions on tail (J:30758)

belly spot ( J:125080 , J:30758 )

head spot ( J:125080 , J:30758 )

abnormal iris stromal pigmentation ( J:30758 )

• less iris pigment than normal

decreased eye pigmentation ( J:125080 )

• iris pigmentation is reduced

vision/eye

abnormal iris stromal pigmentation ( J:30758 )

• less iris pigment than normal

decreased eye pigmentation ( J:125080 )

• iris pigmentation is reduced

hearing/vestibular/ear

abnormal cochlea morphology ( J:125080 )

• no section of the cochlear duct was ever found to be normal

abnormal cochlear hair cell morphology ( J:125080 )

abnormal stria vascularis morphology ( J:125080 )

• abnormal in its entirety

abnormal vestibular saccule morphology ( J:125080 )

• the majority of ears show dedifferentiation and cellular migrations in the cochlear duct and the saccule

nervous system

abnormal cochlear hair cell morphology ( J:125080 )

integument

abnormal coat/hair pigmentation ( J:125080 )

• slight dilution of the fur in the young returns to normal in the adult

white spotting ( J:125080 , J:30758 )

• some, but not all, heterozygotes have a small spot on the head between the eyes and ears or spots on the belly or tail (J:125080)

• white regions on tail (J:30758)

belly spot ( J:125080 , J:30758 )

head spot ( J:125080 , J:30758 )