Phenotypes for Raf1 Tg(Mx1-cre)1Cgn MGI:3511182 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Raf1^tm2Bacc/Raf1^tm2Bacc Tg(Mx1-cre)1Cgn/0
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Raf1^tm2Bacc mutation (2 available); any Raf1 mutation (116 available)
Tg(Mx1-cre)1Cgn mutation (10 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

increased apoptosis ( J:93687 )

• macrophages more sensitive to Salmonella induced apoptosis

• kinetics of apoptosis faster

• specific to Salmonella infection

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24