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Phenotypes Associated with This Genotype
Genotype
MGI:3510548
Allelic
Composition		 Map3k5tm1Hijo/Map3k5tm1Hijo
Raf1tm2Bacc/Raf1tm2Bacc
Tg(Myh6-cre)2182Mds/0
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k5tm1Hijo mutation (4 available); any Map3k5 mutation (63 available)
Raf1tm2Bacc mutation (2 available); any Raf1 mutation (116 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:93418 )
N
• heart size, morphology and function are not significantly different from wild-type unlike Raf1tm2Bacc, Tg(Myhca-cre)2182Mds mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory