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Phenotypes Associated with This Genotype
Genotype
MGI:3053453
Allelic
Composition
Slit3Gt(OST106158)Lex/Slit3Gt(OST106158)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slit3Gt(OST106158)Lex mutation (2 available); any Slit3 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system

muscle
• herniated diaphragm due to a defective central tendon that remained fused to the liver (J:86149)
• herniated diaphragm due to a defective central tendon that remained fused to the liver (J:86149)

renal/urinary system
• various defects affecting some mice (J:86149)
• various defects affecting some mice (J:86149)
• varying degrees of kidney hypoplasia (J:86149)
• varying degrees of kidney hypoplasia (J:86149)
• unilateral or bilateral kidney agenesis observed in some mice (J:86149)
• unilateral or bilateral kidney agenesis observed in some mice (J:86149)

Mouse Models of Human Disease
OMIM ID Ref(s)
Diaphragmatic Hernia, Congenital 142340 J:86149


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory