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Phenotypes Associated with This Genotype
Genotype
MGI:3051565
Allelic
Composition		 Pim2tm1Brn/Pim2tm1Brn
Genetic
Background		 involves: 129P/Ola * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pim2tm1Brn mutation (0 available); any Pim2 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell proliferation ( J:91592 )
• T cell proliferation is reduced in response to suboptimal levels of alphaCD3 and human IL2

hematopoietic system
decreased T cell proliferation ( J:91592 )
• T cell proliferation is reduced in response to suboptimal levels of alphaCD3 and human IL2

cellular
decreased T cell proliferation ( J:91592 )
• T cell proliferation is reduced in response to suboptimal levels of alphaCD3 and human IL2

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory