Phenotypes for Lrp5 Lrp6 MGI:3046423 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lrp5^tm1Jfh/Lrp5⁺ Lrp6^Gt(Ex187)Byg/Lrp6⁺
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp5^tm1Jfh mutation (0 available); any Lrp5 mutation (83 available)
Lrp6^Gt(Ex187)Byg mutation (1 available); any Lrp6 mutation (94 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

forelimb oligodactyly ( J:91055 )

• postaxial digit loss

• typically 1 digit lost on right forelimb

skeleton

abnormal bone ossification ( J:91055 )

• loss of multiple ossification centers

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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