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Phenotypes Associated with This Genotype
Genotype
MGI:3045814
Allelic
Composition		 Jak2tm1Kuw/Jak2tm1Kuw
Tg(Wap-cre)11738Mam/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak2tm1Kuw mutation (1 available); any Jak2 mutation (57 available)
Tg(Wap-cre)11738Mam mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal mammary gland growth during lactation ( J:90883 )
• differentiated mammary epithelia that expressed the Tg(Wap-cre)11738Mam transgene were not maintained during lactation; these Jak2 deficient cells appeared during the first few days of lactation, then were absent for the remainder of the lactation period

integument
abnormal mammary gland growth during lactation ( J:90883 )
• differentiated mammary epithelia that expressed the Tg(Wap-cre)11738Mam transgene were not maintained during lactation; these Jak2 deficient cells appeared during the first few days of lactation, then were absent for the remainder of the lactation period

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory