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Phenotypes Associated with This Genotype
Genotype
MGI:3045411
Allelic
Composition		 Ctnnb1tm1Mmt/Ctnnb1+
Tg(Col2a1-cre)1Bhr/0
Genetic
Background		 involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (51 available)
Tg(Col2a1-cre)1Bhr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, incomplete penetrance ( J:90567 )
• died around E18.5; only 30% survived after birth

skeleton
decreased length of long bones ( J:90567 )
• endochondral bone elements all shorter

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory