Phenotypes for Sh2d1a Tg(DO11.10)10Dlo MGI:3044989 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Sh2d1a^tm1Pls/Sh2d1a^tm1Pls Tg(DO11.10)10Dlo/Tg(DO11.10)10Dlo
Genetic Background	involves: BALB/c * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh2d1a^tm1Pls mutation (4 available); any Sh2d1a mutation (9 available)
Tg(DO11.10)10Dlo mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal cytokine secretion ( J:90484 )

• CD4⁺ T cells produce less IL-4 following treatment with OVA peptide-pulsed antigen presenting cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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