Phenotypes Associated with This Genotype

Genotype
MGI:3044691

• Allelic Composition: Trhr^tm1Bau/Trhr^tm1Bau
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating prolactin level ( J:90365 )

• prolactin levels are 13% and 37% of wild-type in female and male homozygotes respectively

decreased thyroxine level ( J:90365 )

• thyroxine levels are decreased by a factor of 3 in homozygous mice

decreased triiodothyronine level ( J:90365 )

• triiodothyronine levels are decreased by a factor of 3 in homozygous mice

reproductive system

reproductive system phenotype ( J:90365 )

N • despite decreased prolactin levels females become pregnant and successfully raise pups