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Phenotypes Associated with This Genotype
Genotype
MGI:3044078
Allelic
Composition		 Idd13NOD/ShiLt/Idd13NOD/ShiLt
Genetic
Background		 B6.NOD-Idd13
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd13NOD/ShiLt mutation (2 available); any Idd13 mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal NK T cell physiology ( J:85823 )
• defective iNKT cell induced IFN-gamma response
abnormal cytokine secretion ( J:85823 )
• defective cytokine response (IL-2, IL-4, IFN-gamma, CSF-2) when stimulated with antigens

hematopoietic system
abnormal NK T cell physiology ( J:85823 )
• defective iNKT cell induced IFN-gamma response

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory