Phenotypes Associated with This Genotype

Genotype
MGI:3044060

• Allelic Composition: Trp53^tm1Elee/Trp53^tm1Elee; Tg(Wap-rtTA-cre)10Whl/0
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:90247 )

• mean tumor latency about 9.5 months

increased mammary adenocarcinoma incidence ( J:90247 )

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors

• mostly poorly differentiated and invasive

endocrine/exocrine glands

increased mammary adenocarcinoma incidence ( J:90247 )

• mostly poorly differentiated and invasive

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors

integument

increased mammary adenocarcinoma incidence ( J:90247 )

• mostly poorly differentiated and invasive

• all mammalian tumors were adenocarcinomas, myoepithelial adenocarcinomas, adenosquamous carcinomas, or spindle cell tumors