Phenotypes Associated with This Genotype

Genotype
MGI:3044045

• Allelic Composition: Ppp3r1^tm2Grc/Ppp3r1^tm2Grc; Tg(Lck-cre)1Cwi/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

thymus hypoplasia ( J:89771 )

• general decrease in cellularity is observed

decreased thymocyte number ( J:89771 )

• specific reduction in CD4+CD8- and CD4-CD8+ single positive (SP) thymocytes is found

immune system

thymus hypoplasia ( J:89771 )

• general decrease in cellularity is observed

decreased thymocyte number ( J:89771 )

• specific reduction in CD4+CD8- and CD4-CD8+ single positive (SP) thymocytes is found

endocrine/exocrine glands

thymus hypoplasia ( J:89771 )

• general decrease in cellularity is observed

decreased thymocyte number ( J:89771 )

• specific reduction in CD4+CD8- and CD4-CD8+ single positive (SP) thymocytes is found