Mouse Genome Informatics
hm
    Ercc5tm2Shm/Ercc5tm2Shm
involves: 129S2/SvPas * C57BL/6J
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• homozygous mice have a normal lifespan

growth/size/body
N
• homozygous mice do not display any growth abnormalities

homeostasis/metabolism
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cell

integument
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cell

Mouse Models of Human Disease
OMIM IDRef(s)
Xeroderma Pigmentosum, Complementation Group G; XPG 278780 J:89911