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Phenotypes Associated with This Genotype
Genotype
MGI:3043210
Allelic
Composition		 Robo2tm1Mrt/Robo2tm1Mrt
Robo3tm1Matl/Robo3tm1Matl
Genetic
Background		 involves: 129/Sv * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Robo2tm1Mrt mutation (2 available); any Robo2 mutation (102 available)
Robo3tm1Matl mutation (1 available); any Robo3 mutation (76 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon guidance ( J:89438 )
• at E11.5 embryos show no midline crossing and look identical to Robo3tm1Matl homozygous littermates

cellular
abnormal axon guidance ( J:89438 )
• at E11.5 embryos show no midline crossing and look identical to Robo3tm1Matl homozygous littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory