Phenotypes Associated with This Genotype

Genotype
MGI:3043178

• Allelic Composition: hb/hb
• Genetic Background: involves: FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

collapsed Reissner membrane ( J:45223 )

• Reissner's membrane was collapsed throughout the cochlear duct

absent semicircular canals ( J:45223 , J:48656 )

abnormal inner ear vestibule morphology ( J:45223 )

• the vestibular part of the inner ear was present as an extended single cyst

absent cochlear microphonics ( J:45223 )

• no cochlear microphonics could be recorded from the cochlea

absent cochlear nerve compound action potential ( J:45223 )

• no compound action potential could be recorded from the cochlea

deafness ( J:45223 , J:48656 )

behavior/neurological

absent pinna reflex ( J:45223 )

• homozygotes do not display a Preyer's reflex

head bobbing ( J:45223 , J:48656 )

hyperactivity ( J:45223 )

circling ( J:45223 , J:48656 )

nervous system

absent cochlear microphonics ( J:45223 )

• no cochlear microphonics could be recorded from the cochlea

absent cochlear nerve compound action potential ( J:45223 )

• no compound action potential could be recorded from the cochlea