Phenotypes Associated with This Genotype

Genotype
MGI:3042593

• Allelic Composition: Zbtb16^lu/Zbtb16^lu
• Genetic Background: B6.C3-Zbtb16^Lu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

small testis ( J:89934 )

♂ • observed in 8 month old mice; suggested to be due to loss of germ cells

reproductive system

decreased male germ cell number ( J:89934 )

♂ • many seminiferous tubules of older mice were agametic, containing only Sertoli cells; other tubules lacked one or more germ cell generations

azoospermia ( J:89934 )

♂ • observed in 8 month old mice

small testis ( J:89934 )

♂ • observed in 8 month old mice; suggested to be due to loss of germ cells

cellular

decreased male germ cell number ( J:89934 )

♂ • many seminiferous tubules of older mice were agametic, containing only Sertoli cells; other tubules lacked one or more germ cell generations

azoospermia ( J:89934 )

♂ • observed in 8 month old mice