Phenotypes for Crlf2 Jak3 MGI:3039555 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Jak3^tm1Jni/Jak3^tm1Jni Crlf2^tm1Jni/Crlf2^tm1Jni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crlf2^tm1Jni mutation (0 available); any Crlf2 mutation (23 available)
Jak3^tm1Jni mutation (0 available); any Jak3 mutation (85 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal B cell differentiation ( J:89031 )

decreased B cell number ( J:89031 )

• loss of the residual splenic B220⁺ lymphoctyte population that persists in Jak3^tm1Jni homozygotes

immune system

abnormal B cell differentiation ( J:89031 )

decreased B cell number ( J:89031 )

• loss of the residual splenic B220⁺ lymphoctyte population that persists in Jak3^tm1Jni homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/31/2026 MGI 6.24