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Phenotypes Associated with This Genotype
Genotype
MGI:3039502
Allelic
Composition		 Lepob/Lep+
Tg(Apoe-Lepr)1Kry/0
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepob mutation (5 available); any Lep mutation (21 available)
Tg(Apoe-Lepr)1Kry mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
increased total body fat amount ( J:88655 )
• mutants have significantly heavier fat pads compared to non-transgenic littermates

skeleton
increased bone mass ( J:88655 )
• mutants have significantly increased bone mass compared to non-transgenic littermates

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory