Phenotypes Associated with This Genotype

Genotype
MGI:2684842

• Allelic Composition: Bace1^tm1Cdi/Bace1^tm1Cdi
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:86936 )

• spent less time in the center in an open field test and traveled shorter distances

• examined fewer holes in a holeboard exploration test

abnormal anxiety-related response ( J:86936 )

• produced more feces during open field tests

improved righting response ( J:86936 )

• improved righting ability in wire maneuver test

muscle

abnormal muscle physiology ( J:86936 )

• slightly firmer limb tone than in wild-type mice