Phenotypes for Dag1 Tg(GFAP-cre)25Mes MGI:2684282 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dag1^tm1Kcam/Dag1^tm2Kcam Tg(GFAP-cre)25Mes/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dag1^tm1Kcam mutation (1 available); any Dag1 mutation (109 available)
Dag1^tm2Kcam mutation (2 available); any Dag1 mutation (109 available)
Tg(GFAP-cre)25Mes mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal neuronal migration ( J:86901 )

• cerebral, cerebellar and brain stem neuronal migration abnormalities

increased brain size ( J:86901 )

cellular

abnormal neuronal migration ( J:86901 )

• cerebral, cerebellar and brain stem neuronal migration abnormalities

growth/size/body

megacephaly ( J:86901 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
lissencephaly		DOID:0050453	OMIM:PS607432	J:86901

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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