Phenotypes Associated with This Genotype

Genotype
MGI:2682910

• Allelic Composition: L1cam^tm1Fmo/Y; Tg(Camk2a-cre)1Gsc/0
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased exploration in new environment ( J:86626 )

♂

abnormal spatial learning ( J:86626 )

♂ • place learning in a water maze was altered compared to control animals

decreased anxiety-related response ( J:86626 )

♂ • reduced thigmotaxis

hyperactivity ( J:86626 )

♂ • increased movement in a new environment

♂ • enter the open arms of an elevated maze more readily

increased vertical activity ( J:86626 )

♂ • increased rearing in a new environment

nervous system

abnormal CNS synaptic transmission ( J:86626 )

♂ • increased basal synaptic activity in the CA1 region

♂ • larger evoked potentials