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Phenotypes Associated with This Genotype
Genotype
MGI:2682063
Allelic
Composition		 Ext1tm1Yama/Ext1+
Slit2tm1Matl/Slit2tm1Matl
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ext1tm1Yama mutation (0 available); any Ext1 mutation (63 available)
Slit2tm1Matl mutation (2 available); any Slit2 mutation (88 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon guidance ( J:86465 )
• 59-67% of retinal axons project ectopically into the contralateral optic nerve

cellular
abnormal axon guidance ( J:86465 )
• 59-67% of retinal axons project ectopically into the contralateral optic nerve

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory