Phenotypes Associated with This Genotype

Genotype
MGI:2682010

• Allelic Composition: Kitl^Sl-20J/Kitl^Sl-20J
• Genetic Background: C57BL/6J-Kitl^Sl-20J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:86436 )

• no homozygous mice are born

• normal ratio of genotypes at E14.5

growth/size/body

decreased fetal size ( J:86436 )

• homozygous embryos were runted at E14.5

hematopoietic system

abnormal erythropoiesis ( J:86436 )

• reduced CFU-E/BFU-E ratio indicating reduced erythroid progenitors during terminal differentiation

reproductive system

absent primordial germ cells ( J:86436 )

• no primordial germ cells present at E13.5

liver/biliary system

pale liver ( J:86436 )

integument

pallor ( J:86436 )

• fetus pale at E14.5

cellular

absent primordial germ cells ( J:86436 )

• no primordial germ cells present at E13.5