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Phenotypes Associated with This Genotype
Genotype
MGI:2679731
Allelic
Composition		 Cd44tm1.1Ugu/Cd44tm1.1Ugu
Il10tm1Cgn/Il10tm1Cgn
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44tm1.1Ugu mutation (9 available); any Cd44 mutation (73 available)
Il10tm1Cgn mutation (15 available); any Il10 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
weight loss ( J:62867 )
• normal until 24 weeks of age when they start losing weight
• life span normal in spite of weight loss

immune system
abnormal immune system physiology ( J:62867 )
• only small areas of inflammation in the mucosa

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory