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Phenotypes Associated with This Genotype
Genotype
MGI:2677315
Allelic
Composition		 Fgf8tm1.1Mrt/Fgf8tm1.4Mrt
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8tm1.1Mrt mutation (1 available); any Fgf8 mutation (25 available)
Fgf8tm1.4Mrt mutation (0 available); any Fgf8 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:111586 )
• at E10.5 fewer apoptotic cells are detected at the telencephalic midline than in the conditional Fgf8 knockout mice

cellular
decreased neuron apoptosis ( J:111586 )
• at E10.5 fewer apoptotic cells are detected at the telencephalic midline than in the conditional Fgf8 knockout mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory