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Phenotypes Associated with This Genotype
Genotype
MGI:2677148
Allelic
Composition		 Smarca4tm1.2Pcn/Smarca4tm1Mag
Tg(Lck-cre)1Cwi/?
Tg(LCKprBCL2)36Sjk/?
Genetic
Background		 involves: 129S/Sv * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smarca4tm1.2Pcn mutation (1 available); any Smarca4 mutation (110 available)
Smarca4tm1Mag mutation (1 available); any Smarca4 mutation (110 available)
Tg(Lck-cre)1Cwi mutation (3 available)
Tg(LCKprBCL2)36Sjk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
arrested T cell differentiation ( J:85191 )
• cells arrested in G1 phase of cell cycle leading to a 10 fold increase in cell numbers as opposed to animals lacking TgN(LCKprBCL2)36Sjk

immune system
arrested T cell differentiation ( J:85191 )
• cells arrested in G1 phase of cell cycle leading to a 10 fold increase in cell numbers as opposed to animals lacking TgN(LCKprBCL2)36Sjk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory