Analysis Tools
mortality/aging
|
• mice are born in Mendelian ratios but died shortly after birth
|
embryo
|
• disrupted somite development, patterning, and differentiation
• absence of ventral (ribs and vertebrae) and dorsal (skeletal muscle) somite derivatives
|
growth/size/body
|
• newborn pups present with drastically reduced trunk length
|
limbs/digits/tail
|
• rudimentary stump lacking skeletal elements
|
muscle
|
• most skeletal muscles are absent or reduced in size
|
skeleton
absent ribs
(
J:84754
)
