Phenotypes for Cd9 Cd81 MGI:2672816 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Cd81^tm1Tmiy/Cd81^tm1Tmiy Cd9^tm1Mek/Cd9^tm1Mek
Genetic Background	involves: 129/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd81^tm1Tmiy mutation (0 available); any Cd81 mutation (20 available)
Cd9^tm1Mek mutation (0 available); any Cd9 mutation (101 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:83795 )

• mice are viable in spite of smaller body size

hematopoietic system

abnormal definitive hematopoiesis ( J:83795 )

increased osteoclast cell number ( J:83795 )

• 1.5X increase in osteoclast numbers

abnormal macrophage physiology ( J:83795 )

• spontaneous formation of multinucleated giant cells

immune system

increased osteoclast cell number ( J:83795 )

• 1.5X increase in osteoclast numbers

abnormal macrophage physiology ( J:83795 )

• spontaneous formation of multinucleated giant cells

respiratory system

abnormal pulmonary alveolus morphology ( J:83795 )

• alveolar airspace enlargement

skeleton

increased osteoclast cell number ( J:83795 )

• 1.5X increase in osteoclast numbers

decreased bone mineral density ( J:83795 )

abnormal skeleton development ( J:83795 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/13/2026 MGI 6.24